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B12 is a water-soluble vitamin, meaning any excess is quickly flushed out through the urine

Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus

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Multifunctional design The microenvironment of chronic wounds is characterized predominantly by hypoxia, inflammation, and oxidative stress, which impedes angiogenesis, disrupts cellular functions, and decelerates the healing process due to persistent inflammation and an imbalanced redox state

found that in colon cancer, Gln deprivation stimulates p53 activation and promotes the expression of the aspartate/glutamate transporter SLC1A3, thereby promoting glutamate, Gln and nucleotide synthesis, maintaining electron transport chain and tricarboxylic acid cycle activity