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Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease

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Among the drug-induced DNA lesions, abasic (apurinic/apyrimidinic, AP) sites are one of the most common types in cells, and can lead to more deleterious lesions such as DNA strand breaks [4, 5]

Release of these proteins including cytochrome c, s econd m itochondria-derived a ctivator of c aspase (Smac), apoptosis inducing factor (AIF) and endonuclease G have been extensively studied in the context of apoptotic cell death, and it is recognized that the mechanisms of their release may not be identical in all cases