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Topical: 0.1-0.3% serum/cream twice daily for maintenance

Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors

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Third-party HPLC purity and a batch COA: We looked for a recent certificate tied to the exact lot, not a generic purity claim above 99%

Therefore, considering a broad spectrum of effects that may result from the induction of NO synthesis, a deep analysis of its interaction with potent drugs affecting NO pathways should be performed (e.g., aspirin that has been shown to inhibit eNOS [57])