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Eine bermige und anhaltende Stimulation der somatotropen Achse knnte theoretisch Effekte hnlich der Akromegalie hervorrufen: Wasserretention, Arthralgien, Karpaltunnelsyndrom, Insulinresistenz und potenziell ein erhhtes Proliferationsrisiko bestimmter IGF-1-empfindlicher Tumorzellen

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[2] Cell Line:BxPC-3 human pancreatic cancer cells Concentration:10 g/mL Incubation Time:15 min

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At steady state, a KEAP-1 deficiency based persistent activation of NRF2 reduced HSC quiescence without affecting their numbers

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