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When you have low mitochondrial flux, the fuel gets backed up

Impact of adherence to concomitant gastroprotective therapy on nonsteroidal-related gastroduodenal ulcer complications

Therefore, developing and validating biomarkers that directly indicate neuronal ferroptosissuch as specific oxidized phospholipid profiles, ferroptosis-related proteins (e.g., released HMGB1, modified GPX4), or their metabolic fragmentsis crucial for enhancing clinical diagnostic and therapeutic monitoring capabilities

Under-dilution problems Too little water creates the opposite problem

Tran POT, Parker SM, LeRoy E, Franklin CC, Kavanagh TJ, Zhang T, et al