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Suggested Nightly Titration Approach (Educational / Research Reference, Subcutaneous) Starting Dose: Begin with 200 mcg once daily at bedtime to assess tolerance and initial response

In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

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