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High levels of PUFAs are located in the outer photoreceptor segment and produce substantial amounts of intracellular ROS, making the retina especially susceptible to damage from oxidative stress (166) ( Figure 3 )

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1:12 yields remarkable antioxidant capacity (Mort et al., 2008[85])

Cycle Length Considerations The MK-677-024 trial ran for 2 years without loss of IGF-1 efficacy, indicating tachyphylaxis is not a major concern at standard doses [1]

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