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doi: 10.2147/DDDT.S521265 54 FrkW.DbekB.Balcerczyk-LisM.MotorJ.RadziochE.MynarskaE.et al

While all the kynurenines are stable in plasma for at least one year when stored at 80C (145), 3-hydroxykynurenine (HK) and to a larger extent 3-hydroxyanthranilic acid (HAA) decrease significantly in chilled EDTA and heparin blood (147), in serum and plasma at room temperature and in serum at 25C (89)

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The compound's unique -peptide bond between glutamate and cysteine renders it resistant to degradation by common peptidases, allowing intracellular accumulation to protective concentrations