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Patients with B12 deficiency (level below190 pg/ml) were not enrolled due to ethical reasons (patients with established B12 deficiency must be treated and not subjected to randomization)

Depending on your needs, our providers create personalized plans, offering a range of options, including B12 and Vitamin D3 injections and antioxidant support

Injectable dosing regimens (such as 1-2 mg subcutaneously) remain strictly practitioner-reported and research-extrapolated

Furthermore, due to the potential off-target effects of erastin, further investigation is needed to use additional ferroptosis inducers to establish a more robust and comprehensive NSC ferroptosis model

Released NO then acts as a retrograde messenger, amplifying the pain signaling through sustained positive feedback regulation of synaptic plasticity (141)