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The only approved indication of iv Glutathione is as an adjunctive treatment of reduce neurotoxicity associated with cisplatin chemotherapy

This includes enlarged hands, feet, jaw, and internal organ enlargement (for example: heart, liver)

Pharmacological inhibition of TrkB by subchronic intrastriatal administration of k252a rescued behavioral alterations in Bsn mutant mice and prevented the occurrence of pathological form of plasticity in fast-spiking interneurons