This early period of physiologic jaundice has been designated as phase 1 physiologic jaundice

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Here, methionine has emerged as one such sentinel metabolite
Cysteine is synthesized via the transsulfuration pathway, in which homocysteine is first converted to cystathionine by cystathionine-beta-synthase (CBS) and subsequently to cysteine
In addition, senescent melanocytes derived from senescent melanocytes can induce senescence in neighboring cells through paracrine signals involving IP10, CXCR3, and ROS (84)