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It is likely an adaptive stress response induced by a disturbance of homeostasis caused by low levels of biotic or abiotic stimuli (Vargas-Hernandez et al., 2017)

Dawson, M., Wirtz, D

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4-OH-E 2 is capable of binding ER with a reduced dissociation rate and prolonged activation, thereby inducing cellular growth and proliferation, [6] adenohypophyseal hormone secretion, and prostaglandin production

polynucleotide shuffling & interrupted synthesis) and non-stochastic polynucleotide reassembly can be used to further improve the properties, including adjuvant activity, of heat shock proteins, such as HSP70