lysosomal glutathione cystine: an unexpected alarm bell for cysteine scarcity: Trends in Cell Biology Science Note: Lysosome DOJINDO LABORATORIES
Science Note: Lysosome DOJINDO LABORATORIES Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells: Molecular Cell JCI Lysosomal lipid peroxidation regulates tumor immunity A rational design of a cancer specific and lysosome targeted fluorescence nanoprobe for glutathione imaging in living cells Materials Advances (RSC Publishing)
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