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In addition, THC lacks the ,-unsaturated diene structure and consequently exhibits improved solubility, physicochemical stability, and bioavailability compared with curcumin [13, 59]

[7] [8] This triple-receptor mechanism distinguishes it from existing approved agents such as semaglutide (a GLP-1 agonist) or tirzepatide (a dual GLP-1/GIP agonist)