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Advances in microbiome research are opening innovative pathways for probiotic applications, with ongoing clinical studies anticipated to provide significant insights into their effects on human health (2)

However, suppressing AKT activity in Ssu72-deficient adipocytes had only a limited effect on the elevated inhibitory phosphorylation of GSK3 at Ser9, suggesting that GSK3 is the predominant substrate through which Ssu72 regulates -catenin signaling and adipogenic differentiation

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It has been observed to inhibit the hyperactive PI3K/Akt/mTOR pathway, a central regulator of cell growth, survival, and metabolism in many cancers