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This perspective change provided the foundation for the supplement industry that has really exploded over the past century -- the last 50 years especially

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[5] Beyond its antioxidant properties, ALA may serve as an essential cofactor for mitochondrial enzymatic complexes (notably the -ketoacid dehydrogenases) involved in oxidative metabolism

Tissue Eng Part B Rev 28(1):6378 Wang X-J, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT (2008) Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

When you drink, your body converts alcohol into acetaldehyde, an even more toxic compound, before it finally breaks it down into acetate