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Mungroop T, Veelo D, Busch OR, van Dieren S, van Gulik TM, Karsten TM, et al

demonstrated that restoring GSH levels protects against sepsis-induced cardiac dysfunction by inhibiting BNIP3-mediated mitophagy and ferroptosis, preserving mitochondrial function, and reducing lipid peroxidation

Congeners may also slow the metabolism of alcohol, which can prolong your symptoms ( Drinks that are low in congeners include vodka, gin, and rum ( Meanwhile, tequila, whiskey, and cognac are all high in congeners, with bourbon whiskey containing the most ( In one older study, 95 young adults drank enough vodka or bourbon to reach a breath alcohol concentration of 0.11%

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine ( S -n-butyl homocysteine sulfoximine)

H., & Edden, R