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Targeting apoptosis and unfolded protein response: the impact of beta-hydroxybutyrate in clear cell renal cell carcinoma under glucose-deprived conditions

73 In conclusion, the regulation of histone acetylation can provide a new direction for developing aging-delaying approaches

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After 2Y of treatment, liver volumes in most patients were 1.25 multiples of normal (mean reductions: 30% in ASCEND, 49% in ASCEND-Peds, 30% reduction in Phase 1b with 44% reduction after 6.5Y) and mean HDL cholesterol had increased 65% in ASCEND, 137% in ASCEND-Peds, and 115% in Phase 1b (171% increase at 6.5Y)