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(2002) described an increased CSF kynurenine/tryptophan ratio in PD patients

St a dlka ivota jsou ovlivovny adou faktor, z nich uvdme: tlouku karotick intimy a mdie a pomr ku celkov antioxidan kapacit (TAC) / hydroperoxid (HPX): viscerln tukovou tk, nutrin faktory (polynenasycen mastn kyseliny, trans- mastn kyseliny, Fe, vitamin C a pjem karotenoid, kofein, pjem alkohol, historii kouen, fyzickou aktivitu, depresi (stres a zkost), kvalitu spnku a riziko apnoe

Epileptic Disord 22:S10S15 Chen Z et al

Though the protection is localized to the ER, it potentially extends to the cytosol by preventing consumption of reduced glutathione (discussed below), which is a major cytosolic and mitochondrial antioxidant