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4.5.2 CVDs as Victims In general, calcium channel blockers are CYP3A4 substrates and therefore have DDIs with the DAAs that inhibit this enzyme

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The peptide normalized the increased proton leak in cardiomyocytes from old mice, reduced mitochondrial ROS, and improved the early-to-late diastolic filling ratio (Ea/Aa) and myocardial performance index to levels approaching young controls

Notably, the LDM_res model achieves the best performance, with IQD scores 2 orders of magnitude lower than the U-Net and the GAN for 2 m temperature and 1 order of magnitude lower than the GAN for wind speed, highlighting its superior accuracy