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In AD, the brain endothelium releases a precursor substrate for -amyloid plaque and a neurotoxic hormone peptide that kills cortical neurons (Vagnucci and Li 2003)

[3] International Conference on Harmonisation

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Efficacy and safety of Sophora alopecuroides var

Briefly, fresh tissue samples were homogenized in ice-chilled Dounce homogenizers (1:10, w/v) using an isolation buffer and centrifuged at 1000 g for 5 min at 4 C