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[94] [95] Tadalafil, a phosphodiesterase-5 inhibitor, was considered then rejected by NICE in the UK for the treatment of symptoms associated with BPH

Not Comprehensive: May require additional tests (e.g., MMA or homocysteine) to confirm deficiency or rule out false positives

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While many menstrual changes during tirzepatide treatment represent benign adaptive responses to weight loss, certain patterns warrant prompt medical evaluation to exclude other underlying conditions