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Strikingly, we found that TDP-43 SUMOylation was selectively modified by SUMO2 and SUMO3, but not SUMO1, specifically under stressed conditions

2014;9:e93549

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We hypothesized that PAF C-16 and its structurally related compounds may activate macrophages to enhance its intracellular killing ability

considering the strong placebo effect as noted in the rituximab trial, the need for using objective measurements in quantifying stiffness with validated scales were pointed out [100]