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Description

Three reasons compound

Andueza A, Kumar S, Kim J, Kang DW, Mumme HL, Perez JI, Villa-Roel N, Jo H (2020) Endothelial reprogramming by disturbed flow revealed by single-cell RNA and chromatin accessibility study

Attacking ganglion cell death from multiple angles potentially superior to single mechanism

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In this context, their function often overlaps with that of selection biomarkers, as they help enrich trial populations with participants who are more likely to harbor the target pathology