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Iodothyronine deiodinase structure and function: from ascidians to humans

These findings collectively demonstrate that SLE patients exhibit significant gut dysbiosis, characterized by reduced diversity, depletion of beneficial bacteria, and enrichment of potentially pathogenic bacteria such as Streptococcus

But there are also non-genomic actions taking place via the activation of signaling molecules for example phospholipases C and A2, second messengers, activation of protein kinases or opening calcium or chloride channels