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In contrast, PKM2 expression in the liver was markedly reduced in SPTBN1 LSKO mice fed WD and DEN in which NASH and HCC are blocked

Hypercalcemia: Vitamin D is important for helping your body absorb calcium, but high dose vitamin D can lead to elevated calcium levels, also called hypercalcemia

This is in accordance with previous findings that an increase in MDA level due to lipid peroxidation is one of the most common markers of cellular oxidative damage under the heat stress 40

World J Microbiol Biotechnol 30(4):13471357

This matches reports of INH elevating oxidative damage and lipid peroxidation, disrupting redox homeostasis and RBC vulnerability (Figure 4D), linked mechanistically to aberrant Ca2 + influx