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Statements Author contributions BC obtained funding, conceived and designed experiments, analyzed data, proposed model, and wrote the manuscript

This review provides a comprehensive synthesis of current knowledge on adaptive resistance to cancer immunotherapy, with a particular emphasis on the mechanistic contributions of dysfunctional T-cell responses

These results suggest that only flavonol aglycones can affect intestinal bacterial growth, such pattern was observed for other flavonoid glycosides such as flavanones, especially naringenin as described below (Reference Duda-Chodak38)

Bao W, Liu X, Lv Y, Lu GH, Li F, Zhang F, Liu B, Li D, Wei W, Li Y

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