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In these instances, elevated B12 may not be the root cause of illness but a biomarker that may signal a deeper health concern needing investigation

That is how many patients feel on three-monthly injections

The medical world disagrees

Most people tolerate methyl b12 injections very well

Mitophagy is mainly mediated by BCL2/adenovirus E1B 19kDa interacting protein 3/Nip3-like protein X, and Parkin/PINK1 (PTEN induced putative kinase 1) ( 2.2 Immunogenic cell death Immunogenic cell death (ICD), known as immunogenic apoptotic cell death or immunogenic apoptosis, has been defined as a form of regulated cell death that is sufficient to activate an adaptive immune response in immunocompetent hosts ( IR-induced OS can induce immunogenic death of tumor cells through multiple mechanisms ( + T cells and elicited antitumor immunity ( 2.3 Ferroptosis Ferroptosis is another way of radiation-induced tumor cell death, which is caused by lipid peroxidation caused by iron metabolism disorder and ROS accumulation