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7-HMG was the least stable in human plasma (40% 7-HMG remaining after 120 min) with a half-life ( T 1/2 ) of 98.7 min as shown in Figure 1

J., Fusetti, F., Wichers, H

In lupine, melatonin positively regulates root growth within the concentration window of 110 8 to 110 5 M, with 10 M identified as the optimal concentration, whereas 100 M induces growth suppression ( Furthermore, under abiotic stress conditions, the concentration-dependent effects of melatonin become more intricate, being closely modulated by stress types and plant genotypes (Wang et al., 2024)

These early changes are subtle and easily attributed to placebo effect

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