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it helps to regulate and regenerate immune cells, as well as playing a vital role in cellular respiration, detoxification and provides a defence against oxidative stress

The commonality is that vascular damage can be mitigated when the factors contributing to glycocalyx degradation are restored to baseline or brought under control

The link between oxidation and inflammation is complex, going from fine-tuned signaling by ROS during TLR4 activation that leads to active mobilization of damaged-associated molecular patterns, to cellular injury from redox stress that leads to damaged-associated molecular patterns release triggering TLR4-mediated inflammation and organ injury (Gill et al., 2010

Functional enrichment showed that KEGG and GO (BP) were both focused on the cell cycle (Fig