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VEGF, vascular endothelial growth factor

In another rodent experiment, synthetic TB4 was administered to models of autoimmune encephalomyelitis, markedly decreasing the number of inflammatory cells in the brains of the treated animals [39]

There is one small pilot study in humans (examining knee pain, where 7 of 12 participants reported sustained improvement beyond 6 months) and a 2025 safety study confirming BPC-157 was well tolerated in healthy adults