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PMID: 109 VillarDFrostSDeloukasPTinkerA

Preclinical studies investigating KD in HD have primarily used transgenic mouse models, such as the R6/2 mice, which express mutant huntingtin and exhibit progressive motor deficits, weight loss, cognitive impairment, and mitochondrial dysfunction, mimicking central functional and metabolic aspects of HD progression [95, 96]

The levels of Fe 2+ in each of tissue sample were calculated based on this standard curve

Thus, antioxidants surely can hinder oncogenesis by restoring redox balance, preventing DNA damage, regulating DNA methylation status, and repairing damaged DNA