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What happens if I stop HRT

Individuals recruited for a randomized, double-blind, placebo-controlled study were treated with RG (3.0 g/day) or placebo group for 4 weeks and, different parameters, including inflammatory markers, hormones, leukocyte, mtDNA-CN were evaluated

Springer (2004)

Key regulatory axesincluding HIF-1, HHIP-PKM2, PTGES-AKT-HIF-1, and lactate/LDH-A (LDH5)-TGF-interact to collectively promote enhanced glycolysis and diminished oxidative metabolism, sustaining the pathological phenotype of the disease ( Abnormalities in the PPP are primarily manifested as oxidative stress-induced compensatory activation

doi: 10.1007/s12035-024-04127-2 110 NakadateKItoNKawakamiKYamazakiN