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Descalzi, G

Building on these findings, studies have shown that the active mitochondrial network in CRC cells exerts a physical metabolic occupancy effect that impedes immunological synapse formation, while the associated release of ROS further suppresses immune cell function

Authors : Lucie Jett, Roger Lger, Karen Thibaudeau, Corinne Benquet, Martin Robitaille, Isabelle Pellerin, Vronique Paradis, Pieter van Wyk, Khan Pham, Dominique P

It is noteworthy that the disruption of tight junctions is not only a result of inflammation but may also be an early event in the pathogenesis of IBD