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Xie SM, Lai JX, Liu CQ, Zhang XX, Lin YM, Lan QW, Hong DY, Chen XC, Qiao JD, Mao YL (2023) UBR4 deficiency causes male sterility and testis abnormal in Drosophila

555,556 Lifestyle modifications include head-up tilt sleeping, which elevates the head of the bed by 1030 to reduce nocturnal diuresis and improve morning orthostatic tolerance, and advising patients to avoid triggers such as prolonged standing, sudden postural changes, high ambient temperatures, and large meals that may exacerbate symptoms