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10.1016/j.celrep.2014.12.036 [DOI] [PMC free article] [PubMed] [Google Scholar] Wick G., Schett G., Amberger A., Kleindienst R., Xu Q

The ferroptosis pathway involves several critical mechanisms: iron uptake via transferrin receptor, ferritinophagy mediated by nuclear receptor coactivator 4 (NCOA4), iron export through ferroportin regulated by hepcidin, accumulation of lipid peroxides via the Fenton reaction, and antioxidant defense via glutathione peroxidase 4 (GPx4) and glutathione (GSH)

Stockwell et al, 2017)

LPL, Lipoprotein Lipase

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