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[13] [16] For patients taking GLP-1/GIP medicinesparticularly those on concurrent metformin, following restricted diets, or with pre-existing malabsorption conditions proactive monitoring and management of B12 status should be considered an integral component of comprehensive care

These results established cagrilintide as a clinically meaningful agent in its own right, while also confirming that its mechanism was distinct enough from existing therapies to warrant combination investigation

Any disruption to gastric physiology or transit time could theoretically affect this intricate absorption pathway

Welcker M, Clurman BE