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AD AD is marked by progressive cognitive decline linked to extracellular A plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau protein [146]

Cell culture and transfection Drosophila S2R+ cells were maintained at 25C in Schneider medium supplemented with 10% FCS, 10 U/ml penicillin and 10 g/ml streptomycin

non-loaded LTF upstream of Tau phosphorylation and A stimulation would suggest that a pathogen induced shift to a more iron rich LTF could act as a microbial burden sensor, thus enhancing A secretion and Tau phosphorylation to compensate

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