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The evidence base for systemic human applications, however, is not yet at the level required to make confident clinical recommendations which is precisely why the research continues

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On occasion, similar fibroobliterative cholangitis can be seen in 1) PBC, 2) mechanical obstruction of larger bile ducts, 3) ductopenic rejection following liver transplantation, and 4) after intraarterial infusion of 5-fluorouracil