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2023 Dec Anna Andrea Lauer, Heike Sabine Grimm, Birgit Apel, Nataliya Golobrodska, Lara Kruse, Elina Ratanski, Noemi Schulten, Laura Schwarze, Thomas Slawik, Saskia Sperlich, Antonia Vohla, Marcus Otto Walter Grimm, Ben A Bahr

Removal of this loop in class II GRX HsGRX5 had generated an enzyme variant thatin contrast to the wild-typehad detectable reductase activity with roGFP2 (approximately 1.5% of class I HsGRX2) and HED (approximately 0.5% of class I HsGRX2)

Ethyl acetate, acetone, and methanol injections have degraded the separations of last pair of compounds to the point where they are not separated well and will provide low purity for the collected fractions

Safety Considerations: DAC vs No DAC The safety considerations are similar because both act on the GH/IGF-1 axis