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Consistent with this, NNMT knockdown increased 2-DG resistance in PANC-1 cells

The divergent roles of dietary saturated and monounsaturated fatty acids on nerve function in murine models of obesity

SASP includes pro-inflammatory cytokines (IL-6, IL-8, TNF-), growth factors, and matrix metalloproteinases (MMPs), influencing the tissue microenvironment.19 While SASP plays roles in wound healing and tumor suppression, chronic SASP contributes to inflammation, fibrosis, and aging-related diseases.20 Epigenetic Regulation of Senescence: Chromatin remodeling through histone modifications and DNA methylation influences senescence