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Analyses were performed using an Ultimate 3000 HPLC system (Dionex) coupled with a micrOTOF-QII system

Because angiogenesis is a defining hallmark of tumor growth and metastatic progression, any therapeutic agent that enhances neovascularization could, in theory, facilitate tumor expansion and promote metastatic dissemination

Storage Conditions & Handling SOPs Preserving the foundational structural integrity of synthesized peptide solutions requires strict, continuous adherence to established cold-chain protocols to prevent enzymatic degradation or unintended unfolding: Lyophilized Powder Maintenance: Prior to reconstitution, dry chemical vials should be held at a stable temperature of -20C

Supplementary Table S2)

The key components work together to support weight management: Methionine (15mg): An essential amino acid that helps metabolize fat and supports the digestive system Inositol (50mg): Regulates insulin and glucose metabolism while supporting cellular nutrient transfer Choline (100mg): Assists in controlling cholesterol levels and maintaining healthy cell membranes Vitamin B12 (1000mcg): Supports energy metabolism and red blood cell production These nutrients play crucial roles in the body's fat utilization processes, enhancing the liver and gallbladder's function by decreasing fat deposits and accelerating fat metabolism