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10.1016/j.tetlet.2013.04.048 62 ShahrakiO.KhoshneviszadehM.DehghaniM.MohabbatiM.TavakkoliM.SasoL.et al (2020)

GLP-1 monotherapy typically achieves 15-17%

If apoptosis is blocked, necroptosis is triggered through Receptor-Interacting Serine/Threonine-Protein Kinase 1/Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK1/RIPK3)-mediated phosphorylation of Mixed Lineage Kinase Domain-Like Pseudokinase (MLKL), causing membrane rupture and the release of damage-associated molecular patterns (DAMPs) [49]

10.1021/tx010024z 262 SwainU.Subba RaoK

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