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Further to this research has shown that it remains in the body for a longer period of time and at higher levels than cyanocobalamin, which means that your body is supplied with vitamin B12 for longer if you use methylcobalamin than if you use cyanocobalamin
We dont fully understand how, but it seems like this type of B12 could modulate the synthesis of melatonin, a hormone involved in regulating your sleep-wake cycle: Eight young males were subjected to a single blind cross-over test to see the effects of vitamin B12 (methylcobalamin) on the phase-response of the circadian melatonin rhythm to a single bright light exposure
The elderly (reduced absorption) Pernicious anemia Vegetarians / Vegans (low dietary B12) People taking metformin or acid reflux medications (PPIs) Post-bariatric or gastric-bypass patients Genetic variants in MTRR , MTR , or TCN2 What Has B12 Been Studied For
You might be a good candidate for IV Infusion Therapy if: Youre dehydrated after illness, a hangover, or intense exercise