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While some endocrine abnormalities (e.g., hypothalamicpituitary axis dysfunction in GSD I) can be direct consequence of the genetic defect itself, others (e.g., osteopenia in GSD Ib, insulin-resistance in GSD I and GSD III) may be triggered by the (dietary/medical) treatment

When metabolic encephalopathy is clearly documented with its underlying cause , it signals greater clinical complexity and can move the case into a higher-weighted DRG

Mice were injected with LAAM GSH-CQDs (5 mg kg 1 ) via tail vein injection ( n = 3)

The chilling of adenylyl cyclase 9 and its translational potential

Oncogene 26 , 12221230 (2007)