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Since it has a long history of clinical use, its side effects are well known (Pacher et al., 2006)

Neuropeptides 67, 95101

From a therapeutic standpoint, pharmacological inhibition of SLFN4 either through small molecules like sildenafil or genetic approaches has demonstrated efficacy in preclinical models

[DOI] [PMC free article] [PubMed] [Google Scholar] 98.GluN2A and GluN2B N-methyl-D-aspartate receptor (NMDAR) subunits: their roles and therapeutic antagonists in neurological diseases