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In an example application as an anti-infective lock solution for intravascular catheters, the GSNO-CD solution exhibits potent antibacterial activities for both planktonic and biofilm bacteria, both intraluminal and extraluminal environments, both prevention and treatment of infections, and against multiple bacterial strains including a multidrug-resistant strain

Although still in early development, CAAR T therapy may hold particular promise for patients with refractory CLE in the context of systemic involvement

The activity of amino acid transporters is tightly regulated to ensure the proper balance of amino acids needed for various physiological processes

Many drugs, including antibiotics, anti-inflammatories, chemotherapeutics, antipsychotics, and others, have demonstrated cytotoxic effects on erythrocytes

As AIP is a potent competitive PAL inhibitor, the buildup of phenylalanine without increased PAL activity likely explains the observed effects