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This enzyme metabolizes many medications, creating opportunities for drug interactions

doi: 10.1038/sj.cdd.4401910 64 BykovVErikssonSEBianchiJWimanKG

The results of subcellular localization analysis showed proteins of the Euphorbiaceae GST supergene family to be widely distributed, namely in the cytoplasm, plasma membrane, mitochondrion, chloroplast, periplasm, adventitia and extracellular regions

Furthermore, PD patients with diabetes exhibited higher subscores for postural instability and gait difficulties after controlling for dopaminergic denervation in the SN and striatum ( t = 3.81, P = 0.0005) [32] Apart from motor symptoms, PD is characterized by a wide variety of non-motor features, including dementia, depression, sleep disturbance, orthostatic hypotension, and psychotic symptom [1]