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Ozempic is contraindicated in patients with a family history of medullary thyroid cancer (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

All experiments were conducted in compliance with relevant guidelines and regulations approved by the Institutional Animal Care and Use Committee (ICAUC) at the University of Kansas Medical Center

In addition to directly obtaining TMAO from fish and seafood, it is more commonly produced by the gut microbiota through the conversion of foods rich in choline, L-carnitine, and ergothioneine (e.g., red meat, eggs, and mushrooms) (164)