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Efficacy and safety of reduced-dose versus full-dose direct oral anticoagulants for extended treatment of venous thromboembolism: A meta-analysis with trial sequential analysis and reconstructed time-to-event data

for conducting the next-generation sequencing and assisting with the data acquisition, ELSS, Inc for proofreading and editing the English language of this manuscript, Bloomington Drosophila Stock Centre for providing the Drosophila stocks used in this study, and Japan Collection of Microorganisms RIKEN BioResource Research Centre for providing the bacterial strains used in this research

While MEM treatment primarily promotes the synthesis of coenzymes associated with energy metabolism and amino acid metabolism, AMP treatment exhibits a significant enhancement of polyamine metabolism, which plays a critical role in cell growth and proliferation under stress conditions